Tuberculosis (<i>Mycobacterium marinum </i>)


Muscular atrophy
Muscles of fish show evident wasting away.
Anterior-posterior curvature of the spine
Lateral curvature of the spine.
Haemorrhages - skin
Bloody haemorrhages are apparent over several parts of the skin.
Ulcers - irregular
Irregular shaped ulcers are evident on the skin.
Abdomen sunken
The lower part of the fish's body is hollow and wasted.
Exophthalmia - bilateral
Both eyeballs of fish are protruding.
Growth poor
Parasite infested fish show very slow or no growth, as parasite is taking the food.
Loss of membrane & rays
Fins are eaten away, both the rays & the interstitial membranes between
Haemorrhagic Eyes
Eyes are shot with bloody lines.
Hiding abnormally
Fish hides behind rocks or suchlike, appearing seldom if ever.
Listless and lethargic
Fish moves very lazily in water, much less than normal, lacks interest.
Loss of balance
Fish keeps falling from its attempted swimming pattern.
Reluctant to feed
Fish comes to eat but with evident lack of appetite.


Mycobacteria spp. worldwide. All fish species are succeptible.


Very infectious indeed, and will cause major losses. No effective treatment.


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DNA and RNA diagnostic references

The pathogen Mycobacterium marinum, a faster growing close relative of Mycobacterium tuberculosis, has a single rRNA operon per genome. 

From FEMS Microbiol Lett. 2004 Jun 15; 235(2) 281-8

Helquero-Repetto C. Departamento de Microbiologia, Escuela Nacional de
Microbiologia, Escuela Nacional de Ciencias Biológicas, IPN., Prolongación
Carpio y Plan de Ayala S/N, Col. Santo Tomas, México 11340 DF, Mexico


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